3 mins. read

Understanding changes in memory and concentration

Find out about Cancer Related Cognitive Impairment, including its causes, symptoms and impact

Key takeaways

  • ‘Cancer Related Cognitive Impairment or CRCI can affect up to three quarters of people with cancer
  • CRCI can be caused by cancer and its treatment, as well as psychosocial factors such as stress
  • People who experience CRCI often struggle with memory and concentration, word-finding and multi-tasking
  • CRCI can have a negative impact on a person’s quality of life, relationships and work

Changes to memory and concentration after cancer treatment is known as Cancer Related Cognitive Impairment or CRCI or you may have heard it referred to as brain fog. CRCI can affect up to three quarters of people after a cancer diagnosis. Although symptoms usually get better after treatment, unfortunately, for some they can last longer, however they don’t tend to get worse. Changes to memory and concentration can have a negative impact on a person’s quality of life. In this article, our Perci professionals share their approaches to supporting members through this frustrating side-effect of cancer and its treatment.


What causes Cancer Related Cognitive Impairment?

The causes of CRCI are not fully understood, but a combination of factors could contribute to the symptoms. These include cancer and cancer treatment, factors relating to the individual – such as genetics, lifestyle and other medical issues – and other cancer-related side-effects, including anxiety, cancer-related fatigue, hormone imbalances, pain and feeling unwell.

What are the symptoms of CRCI?

CRCI can be experienced in different ways. These include:

  • Memory loss, such as forgetting names or dates
  • Difficulty maintaining attention, such as being unable to concentrate on work tasks or conversations
  • Word finding difficulties
  • Difficulty multitasking carrying out complex tasks in order, such as organising schedules or making a meal
  • Disorientation

What impact might CRCI have on your life?

People experiencing CRCI often find themselves getting frustrated or agitated. They might have trouble making decisions, following conversations or dealing with everyday situations, and might find that they make more mistakes than normal. This can lead to a loss of confidence, feelings of isolation, anxiety or low mood. 

All of these factors can have an impact on quality of life and relationships, everyday activities and also on decisions about returning work and coping when you have returned. It’s important to remind yourself that CRCI is a common side-effect of cancer treatment and that you are not alone. 

Remember that for many people, CRCI resolves sometime after cancer treatment. However, for others it can continue, and it becomes necessary for them to find a way to manage it in their day-to-day life. Do not be afraid to ask for support from your treatment or follow-up team.

While we have ensured that every article is medically reviewed and approved, information presented here is not intended to be a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns, please talk to one of our healthcare professionals or your primary healthcare team.